Microbial Screening offers innovative solutions to biodiscovery and novelty with a range of services, including critical support in dereplication and fermentation. The key to efficiency in biodiscovery is to understand and quickly recognise what is known and focus on what is novel. We have developed tools to enable us to rapidly and efficiently explore biodiversity.

Microbial Screening can tailor access to microbial chemical diversity to suit both small and large clients commensurate with their needs.

Libraries of microbial cultures can cater for a broad or narrow focus:
  • "Raw" cultures produced using selected, innovative isolation strategies,
  • Cultures pre-screened for specific biological activity profiles,
  • Talented strains chosen for their metabolic dexterity,
  • High producing strains for ease of scale-up fermentation.
Collections of extracts are available at various levels of refinement, ready for integration into your screening program:
  • Crude extracts as bulk samples in vials or microtitre plate format,
  • Solid phase-partitioned, enriched fractionated libraries of secondary metabolite mixtures,
  • Highly refined HPLC fractionated libraries of secondary metabolites,
  • Pure microbial metabolites comprising rare and novel natural products
Located in Sydney, Australia, Microbial Screening's state-of-the-art laboratories feature all the facilities required to undertake a full natural product discovery program from microbial isolation and high throughput screening, to scale-up fermentation, isolation chemistry and structure elucidation. We offer a full range of services either on a contract basis or as part of a broader collaborative venture. These include:
  • High-throughput Bioassay Platforms
  • Large-scale fermentation
  • Strain improvement
  • State-of-the-art preparative reverse phase HPLC
  • 2D NMR based structure elucidation
All our products are backed by our dereplication process, in-house databases and quality control.

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