Benjamin R. Clark, Robert J. Capon, Ernest Lacey, Shaun Tennant, and Jennifer H. Gill
Organic Letters, 2006, 8, 701-704.
Publication Date: January 19, 2006
https://doi.org/10.1021/ol052880y
Abstract:
An Australian isolate of the soil ascomycete Gymnoascus reessii yielded a series of cytotoxic metabolites, including the known polyenylpyrroles rumbrin (1) and auxarconjugatin A (2), and the new rumbrin stereoisomer 12E-isorumbrin (3), as well as an unprecedented class of polyenylfurans exemplified by gymnoconjugatins A (4) and B (5). Structures were assigned with detailed spectroscopic analysis.