Samuele Sala, Jane Fromont, Oliver Gomez, Daniel Vuong, Ernest Lacey, and Gavin R. Flematti
J. Nat. Prod. 2019, 82, 3450-3455.
Publication Date: December 13, 2019
https://doi.org/10.1021/acs.jnatprod.9b00840
Abstract:
Seven new nitrile-bearing polyacetylenes, named albanitriles A–G, were isolated from a marine sponge of the Mycale genus (Order: Poecilosclerida, Family: Mycalidae) collected near Albany, Western Australia. Structural elucidation was achieved using a combination of high-resolution mass spectrometry and ultraviolet/visible, infrared, and nuclear magnetic resonance spectroscopy. The compounds were found to possess moderate activity against Giardia duodenalis when compared to a metronidazole positive control.
