Robert J. Capon,Colin Skene,Edward H. Liu,Ernest Lacey,Jennifer H. Gill,Kirstin Heiland & Thomas Friedel
Natural Product Research, 18: 305-309.
Publication Date: August 19, 2003
https://doi.org/10.1080/14786410310001620619
Abstract:
Bioassay directed fractionation of a Raspailia (Raspailia) sp. (Order Poecilosclerida; Family Raspailiidae) collected during scientific trawling operations off the Northern Rottnest Shelf yielded as nematocidal agents the known metabolites, phorboxazoles A (1) and B (2). Further examination revealed the new natural product but known synthetic compound, esmodil (3). The structure for 3 was confirmed by spectroscopic analysis and total synthesis.